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أبحاث الدكتور آن يي هوا للخلايا الجذعية

برامج الأبحاث

  • Development of stem cell technology and products for treating cerebrovascular disease sequelae. National 863 Stem Cell and Tissue Engineering project (2006AA02A115):
  • Experimental research on neural stem cell transplantation to treat temporal lobe epilepsy. Nature Science Foundation of China (30240052)
  • Experiment and clinical research on traumatic brain injury and treatment with mild hypothermia. The 9th Five-Year Key Project of Heilongjiang Province（G98L19-13)

البرامج البحثية الممولة

  • Neural stem cell transplantation to repair dysfunction after cerebral infarction in monkeys. The 10th Huo Yingdong Education Foundation Fellowship for Young Teachers of Higher Education (101043)
  • Research on the underlying mechanism of neural stem cell transplantation to treat motor neuron disease. The New-Century Notable Talent Culture Plan of the Chinese Ministry of Education
  • Combination of neural stem cells and tissue engineering to treat post-cerebral hemorrhage neurological dysfunction in monkeys.Nature Science Foundation of China (30371452)
  • Combination of neural stem cells and tissue engineering to repair facial nerve injury.Nature Science Foundation of Beijing City (30371452)
  • Combination of neural stem cells and tissue engineering to treat post-cerebral hemorrhage neurological dysfunction. Beijing New Star of Science and Technology Culture Plan (H020821360130)
  • Combination of neural stem cells and tissue engineering to treat post-cerebral hemorrhage neurological dysfunction in monkeys. International science and technology cooperation project of Beijing in 2003（2003012)
  • Neural stem cell transplantation to repair post-cerebral hemorrhage dysfunction in rats. Beijing Notable Talent Culture Project
  • Preclinical research on neural stem cell transplantation to treat stroke sequelae. China Postdoctoral Foundation
  • Culture and transplantation of human multipotent  neural stem cells: a pilot study. Beijing Young Research Culture Foundation
  • Preclinical and clinical study on the relationship between free radicals and delayed secondary brain injury after hypothermia protection. Research Foundation for Young Scientists (Heilongjiang Province) (Q99-19)

الأبحاث التي تم نشرها عن الخلايا الجذعية

  • Modulation and impact of class I major histocompatibility complex by neural stem cell-derived neurotrophins on neuroregeneration.  (Medical Hypotheses. 2007, 68: 176–179)
  • Induction of functional recovery by co-transplantation of neural stem cells and Schwann cells in a rat spinal cord contusion injury model.  (Biomedical and environmental sciences. 2007, 20: 242–249)
  • Magnetic resonance tracking of transplanted neural stem cells labeled with superparamagnetic iron oxide nanoparticles in ischemic rat. (Chin J radiol. 2006, 40(2): 122–126)
  • Co-transplantation of neural stem cells and Schwann cells to repair spinal cord injury in rats. (Chin J Exp Surg. 2006, 23(2): 214–215)
  • A model of focal cortical infarction in rat: minimally invasive craniotomy. (Chin J Rehabil Theory Practice.2006, 12(1): 11–14)
  • Potential of stem cell based therapy and tissue engineering in the regeneration of the central nervous system. (Biomed Mater, 2006, 1: 38–44)
  • Induction of endogenous neural stem cells with hyperbaric oxygen after half cut-off of spinal cord in rats. (Chin J Rehabil Theory Practice.2006, 12(5): 369–371)
  • Clinical analysis of neural stem cells for treatment of sequelae in 50 stroke patients. (Chinese J Clin Rehab. 2006, 10(9): 138–139)
  • Magnetic resonance tracking of magnetically-labeled rat embryonic neural stem cells after transplantation. (Radiol practice. 2006, 21(2): 110–113)
  • A model of focal cerebral infarction in the rat: minimally invasive craniotomy. (Chin J Rehabil Theory Practice. 2006, 12(1): 11–14)
  • A model of focal cerebral infarction in the rat for the study of neural stem cell transplantation. (Chin J Cerebrovasc Dis. 2006, 3(1):34–37)
  • Differentiation of rat bone marrow stromal cells into an osteogenic phenotype. (Chin J Rehabil Theory Practice. 2005, 11(12): 999–1110)
  • Experimental study of a rat cerebral hemorrhage model via autologous blood injection. (Chin J Rehabil Theory Practice. 2004, 10(6): 346–347)
  • Ultrastructure of neural stem cells of Wistar rats cultured in vitro. (Chin J Rehabil Theory Practice. 2004, 10(1): 11–12)
  • Research on repairing facial nerve injury of rabbits by neural stem cells and autologous fascia. (Chin J Rehabil Theory Practice. 2004, 10(1): 21–23)
  • Effect of combined therapy consisting of mild hypothermia and hibernation on severe brain injury. (Chin J Rehabil Theory Practice. 2004, 10(3): 181–182)
  • Differentiation of rat neural stem cells and its relationship with environment. (Biomedical and environmental sciences. 2004, 17: 1–7)
  • Transplantation of neural stem cells improved the neurological function of cerebral ischemic rats. (Chin J Exp Surg. 2003, 20(8): 697–699)
  • Temporal expression of nestin in differentiated neural stem cells. (Chin J Exp Surg. 2003, 20(9): 838–840)
  • Cultivation differentiation and its characteristics in rat spinal cord-derived neural stem cells. (Chin J Neurosurg. 2003, 19(2): 135–137)
  • Effect of rat Schwann cell secretion on proliferation and differentiation of human neural stem cells. (Biomedical and environmental sciences. 2003, 16: 90–94)
  • Comparison of neural stem cell differentiation induced by serum supplementation and Schwann cell co-culture. (J Apoplexy and nervous diseases. 2003, 20(5): 388)
  • Lack of immune rejection following intracerebral transplantation of heterogenous neural stem cells in rats. (Chin J rehabil theory practice. 2003, 9(9): 541–542)
  • The proliferation and migration of neural precursor cells in the adult rat brain following fluid percussion injury in vivo. (Chin J Neurosurg. 2002, 18(5): 298–301)
  • Rat embryonic neural stem cell transplantation to treat intracerebral hemorrhage. (Chin J Neurosurg. 2002, 18(1): 50–53)
  • Growth and differentiation of human embryonic neural stem cells boosted by rat Schwann cells. (Chin J Neurosurg. 2002, 18(5): 279–281)
  • Differentiative fates of rat neural stem cells differ in various circumstance. (Chin J Neurosurg. 2002, 18(5): 275–278)
  • Differentiation of embryonic neural stem cells promoted by co-cultured Schwann cells. (Chin J Neurosurg. 2002, 18(2): 100–103)